Back to Search
Start Over
PIK3CA Genotype and Treatment Decisions in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
PIK3CA Genotype and Treatment Decisions in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
- Source :
- Journal of Clinical Oncology. 33:1318-1321
- Publication Year :
- 2015
- Publisher :
- American Society of Clinical Oncology (ASCO), 2015.
-
Abstract
- Genotyping of patient tumors has been rapidly incorporated into both clinical trials and clinical practice over the last several years, with the goal of advancing personalized or precision cancer medicine. The crux of these efforts is to identify actionable alterations— genetic changes that can be used to guide individualized treatment. Dramatic advances in sequencing technologies and DNA isolation methods now enable multiplex hotspot mutation testing or targeted exome se
- Subjects :
- Cancer Research
Mutation
Receptor, ErbB-2
business.industry
Breast Neoplasms
ORIGINAL REPORTS
Antibodies, Monoclonal, Humanized
Bioinformatics
medicine.disease
medicine.disease_cause
Clinical trial
Phosphatidylinositol 3-Kinases
Breast cancer
Oncology
Antineoplastic Combined Chemotherapy Protocols
Genotype
Monoclonal
Humans
Medicine
Female
Multiplex
business
Exome
Genotyping
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....831195254f20ee3c03fdadd033f7f9a6
- Full Text :
- https://doi.org/10.1200/jco.2014.59.3160