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Biomarkers in acute respiratory distress syndrome
- Source :
- Current opinion in critical care. 20(1)
- Publication Year :
- 2013
-
Abstract
- The article provides an overview of efforts to identify and validate biomarkers in acute respiratory distress syndrome (ARDS) and a discussion of the challenges confronting researchers in this area.Although various putative biomarkers have been investigated in ARDS, the data have been largely disappointing and the 'troponin' of ARDS remains elusive. Establishing a relationship between measurable biological processes and clinical outcomes is vital to advancing clinical trials in ARDS and expanding our arsenal of treatments for this complex syndrome.This article summarizes the current status of ARDS biomarker research and provides a framework for future investigation.
- Subjects :
- Male
Vascular Endothelial Growth Factor A
medicine.medical_specialty
ARDS
Ventilator-Induced Lung Injury
Receptor for Advanced Glycation End Products
MEDLINE
Vesicular Transport Proteins
Acute respiratory distress
Critical Care and Intensive Care Medicine
Plasminogen Activator Inhibitor 1
von Willebrand Factor
medicine
Humans
Intensive care medicine
Respiratory Distress Syndrome
business.industry
Interleukin-6
Tumor Necrosis Factor-alpha
Research
Interleukin-8
Mucin-1
medicine.disease
Intercellular Adhesion Molecule-1
Respiration, Artificial
Female
business
Biomarkers
Subjects
Details
- ISSN :
- 15317072
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Current opinion in critical care
- Accession number :
- edsair.doi.dedup.....833784dcead25daace2b69e15b2605f4