Back to Search
Start Over
Quantitative assessment of the presence and severity of cirrhosis in patients with hepatitis B using right liver lobe volume and spleen size measured at magnetic resonance imaging
- Source :
- PLoS ONE, PLoS ONE, Vol 9, Iss 3, p e89973 (2014)
- Publication Year :
- 2013
-
Abstract
- Objective To determine whether right liver lobe volume (RV) and spleen size measured utilizing magnetic resonance (MR) imaging could identify the presence and severity of cirrhosis in patients with hepatitis B. Methods Two hundred and five consecutive patients with clinically confirmed diagnosis of cirrhosis due to hepatitis B and 40 healthy control individuals were enrolled in this study and underwent abdominal triphasic enhanced scans using MR imaging. Spleen maximal width (W), thickness (T) and length (L), together with RV and spleen volume (SV), were measured utilizing MR imaging. Spleen multidimensional index (SI) was obtained by multiplying previously acquired parameters W×T×L. Then statistical assessment was performed to evaluate the ability of these parameters, including RV, SV, RV/SV and SI, to identify the presence of cirrhosis and define Child-Pugh class of this disease. Results SV and SI tended to increase (r = 0.557 and 0.622, respectively; all P
- Subjects :
- Liver Cirrhosis
Male
Pathology
Cirrhosis
Epidemiology
Gastroenterology and hepatology
lcsh:Medicine
Gastroenterology
Diagnostic Radiology
Medicine
Clinical Epidemiology
lcsh:Science
Aged, 80 and over
Observer Variation
Multidisciplinary
medicine.diagnostic_test
Organ Size
Hepatitis B
Middle Aged
Magnetic Resonance Imaging
Healthy Volunteers
Infectious hepatitis
medicine.anatomical_structure
Liver
Female
Radiology
Research Article
Adult
medicine.medical_specialty
Clinical Research Design
Spleen
Diagnostic Medicine
Internal medicine
Humans
In patient
Liver diseases
Aged
Right liver lobe
Receiver operating characteristic
business.industry
lcsh:R
Case-control study
Magnetic resonance imaging
medicine.disease
ROC Curve
Case-Control Studies
lcsh:Q
business
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 9
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- PloS one
- Accession number :
- edsair.doi.dedup.....8353a0742493dd9159e04316c505c92a