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Later puberty onset among chronically undernourished adolescents living in a Karachi slum, Pakistan
- Source :
- Acta paediatrica (Oslo, Norway : 1992)REFERENCES. 109(5)
- Publication Year :
- 2019
-
Abstract
- Aim To assess factors associated with the timing of puberty onset (Tanner Stage Breast 2/Genital 2) among adolescents living in an urban slum in Karachi, Pakistan. Methods Girls enrolled at 8-10 years (n = 1009) and boys 9-11 years (n = 863) were followed every 6 months from 2006 to 2010. Parametric survival analysis for interval-censored data was used to estimate median age at puberty onset and assess the association between exposures and timing of puberty onset. Results The overall median age at Tanner Stage Breast 2 (AAB2) was 10.1 years (95% CI: 10.1; 10.5), and the median age at Tanner Stage Genital 2 (AAG2) was 10.1 years (95% CI: 10.1; 10.6). Stunting delayed AAB2 1 year and AAG2 about 6 months when compared to non-stunted peers. In the multivariable model, after adjusting for age at enrolment, stunting, thinness and vitamin A deficiency (VAD) were significantly associated with delayed AAB2, while stunting and anaemia were significantly associated with delayed AAG2. Conclusion Among adolescents living in the Karachi slum, stunting and highly prevalent anaemia delayed AAG2, while stunting, thinness and VAD delayed AAG2. Parental and household factors were not significantly associated with the timing of puberty onset.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Adolescent
03 medical and health sciences
0302 clinical medicine
Thinness
030225 pediatrics
Poverty Areas
Medicine
Humans
Sex organ
Pakistan
030212 general & internal medicine
Survival analysis
business.industry
Puberty
General Medicine
Micronutrient
medicine.disease
Vitamin A deficiency
Malnutrition
Cross-Sectional Studies
Pediatrics, Perinatology and Child Health
Urban slum
Female
business
Slum
Puberty onset
Subjects
Details
- ISSN :
- 16512227
- Volume :
- 109
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Acta paediatrica (Oslo, Norway : 1992)REFERENCES
- Accession number :
- edsair.doi.dedup.....836c9c09b9cbef7b3c8b9fcd724cff4e