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An Application of a Service-oriented System to Support ArrayAnnotation in Custom Chip Design for Epigenomic Analysis
- Source :
- Cancer Informatics, Vol 6, Pp 111-125 (2008)
- Publication Year :
- 2008
- Publisher :
- SAGE Publishing, 2008.
-
Abstract
- We present the implementation of an application using caGrid, which is the service-oriented Grid software infrastructure of the NCI cancer Biomedical Informatics Grid (caBIG™), to support design and analysis of custom microarray experiments in the study of epigenetic alterations in cancer. The design and execution of these experiments requires synthesis of information from multiple data types and datasets. In our implementation, each data source is implemented as a caGrid Data Service, and analytical resources are wrapped as caGrid Analytical Services. This service-based implementation has several advantages. A backend resource can be modified or upgraded, without needing to change other components in the application. A remote resource can be added easily, since resources are not required to be collected in a centralized infrastructure.
- Subjects :
- 0303 health sciences
Cancer Research
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
grid computing
lcsh:RC254-282
03 medical and health sciences
0302 clinical medicine
Oncology
030220 oncology & carcinogenesis
service oriented architectures
caBIG and caGrid
data integration
epigenetic studies
030304 developmental biology
Subjects
Details
- Language :
- English
- ISSN :
- 11769351
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Cancer Informatics
- Accession number :
- edsair.doi.dedup.....836cf59b45bbe9d4fa85046821d1f8d3