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Performance of routine assessment of patient index data 3 (RAPID3) in monitoring disease activity of Chinese rheumatoid arthritis patients
- Source :
- International journal of rheumatic diseases. 21(11)
- Publication Year :
- 2018
-
Abstract
- To explore the performance of routine assessment of patient index data 3 (RAPID3) in reflecting disease activity in Chinese rheumatoid arthritis (RA) patients.The clinical data of 189 consecutive RA patients, including RAPID3 questionnaire, Disease Activity Score based on 28-joint count (DAS28), clinical disease activity index (CDAI) and simplified disease activity index (SDAI), and ultrasonography of hand and wrist joints were collected. The consistency between RAPID3 and DAS28, CDAI, SDAI in RA patients with different disease activities was performed by Spearman's correlations, kappa and/or weighted kappa coefficients.RAPID3 score was significantly associated with DAS28 and erythrocyte sedimentation rate (ESR), DAS28 with C-reactive protein (CRP), CDAI, SDAI (r = 0.797, 0.786, 0.784, and 0.760 respectively, P 0.001 for all). RAPID3 was also significantly correlated with tender joint count, swollen joint count, ESR and CRP. The agreement of RAPID3 with DAS28 scoring systems was better in patients with moderate/high disease activity than those in remission/low disease activity. Ultrasonographic subclinical synovitis was presented in 42.3%-48.6% of patients in remission/low disease activity defined by various scoring criteria including RAPID3 with no significant difference observed (P = 0.22,0.05).RAPID3 showed good correlation with DAS28 scoring systems, especially in patients with moderate/high disease activity. RAPID3 is a reliable and convenient tool to monitor disease activity.
- Subjects :
- musculoskeletal diseases
Adult
Male
medicine.medical_specialty
China
Disease
Blood Sedimentation
Severity of Illness Index
Disease activity
Arthritis, Rheumatoid
03 medical and health sciences
0302 clinical medicine
Rheumatology
Wrist joints
Predictive Value of Tests
Internal medicine
Surveys and Questionnaires
medicine
Humans
030212 general & internal medicine
skin and connective tissue diseases
Aged
Ultrasonography
030203 arthritis & rheumatology
Synovitis
medicine.diagnostic_test
business.industry
Reproducibility of Results
Simplified disease activity index
Middle Aged
Clinical disease
medicine.disease
Prognosis
C-Reactive Protein
Erythrocyte sedimentation rate
Rheumatoid arthritis
Female
Joints
Self Report
Inflammation Mediators
business
Kappa
Biomarkers
Subjects
Details
- ISSN :
- 1756185X
- Volume :
- 21
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- International journal of rheumatic diseases
- Accession number :
- edsair.doi.dedup.....83fc621418e23914dbb9b8ff64764139