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Environmental factors and their timing in adult-onset multiple sclerosis
Environmental factors and their timing in adult-onset multiple sclerosis
- Publication Year :
- 2016
- Publisher :
- Macmillan Publishers Ltd., 2016.
-
Abstract
- Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data implicate both genetic and environmental factors in the etiology of MS, with various factors interacting with one another. Environmental exposures might occur long before the disease becomes clinically evident, as suggested by the wide range in onset age. In this Review, we examine the key time periods during which the environment might contribute to MS susceptibility, as well as the potential environmental factors involved. Understanding the nature of environmental influences in MS is highly relevant to the development of public health measures that are aimed at preventing this debilitating disease.
- Subjects :
- medicine.medical_specialty
Time Factors
Multiple Sclerosis
Disease
Environment
Bioinformatics
Disease activity
Cellular and Molecular Neuroscience
Risk Factors
Epidemiology
medicine
Animals
Humans
Serum 25 hydroxyvitamin d
business.industry
Multiple sclerosis
Public health
Environmental Exposure
medicine.disease
Clinical neurology
Immunology
Etiology
Neurology (clinical)
Disease Susceptibility
business
Neuroscience
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....840ec1a6ed0afe03c07507697b2c0f7a
- Full Text :
- https://doi.org/10.1038/nrneurol.2010.1