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Stimulation of limb regeneration in the lizard Xantusia vigilis by means of ependymal implants
- Source :
- The Journal of experimental zoology. 189(3)
- Publication Year :
- 1974
-
Abstract
- The experiments reported in this paper demonstrate that ependymal cells can stimulate a regenerative outgrowth when implanted into the limb of a lizard. Simple limb amputation, amputation followed by a sham operation, and amputation followed by the implantation of a cartilage tube from a tail regenerate were ineffective in causing the hind limbs of Xantusia vigilis to regenerate. However, amputation followed by the implantation of a cartilage tube containing ependyma caused regenerative outgrowths in 82% of the treated limbs. These results show that ependymal cells, in addition to initiating tail regeneration in their normal location, can when transplanted to the limb, initiate limb regeneration.
- Subjects :
- Tail
Ependymal Cell
medicine.medical_treatment
Hindlimb
Amputation, Surgical
Ependyma
medicine
Animals
Regeneration
Transplantation, Homologous
Xantusia vigilis
biology
Regeneration (biology)
Cartilage
Lizards
General Medicine
Anatomy
biology.organism_classification
Spinal cord
body regions
medicine.anatomical_structure
Amputation
Spinal Cord
Animal Science and Zoology
Subjects
Details
- ISSN :
- 0022104X
- Volume :
- 189
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The Journal of experimental zoology
- Accession number :
- edsair.doi.dedup.....84605275f0eb3c3afa05a92ff820668a