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Bone quality assessment by quantitative ultrasound of proximal phalanxes of the hand in healthy subjects aged 3--21 years
- Source :
- Pediatric research. 49(5)
- Publication Year :
- 2001
-
Abstract
- Bone quality by quantitative ultrasound was assessed in 1083 (587 males) healthy white subjects aged 3--21 y. Amplitude-dependent speed of sound (AD-SoS) through the distal end of the first phalanx diaphysis of the last four fingers of the hand was measured by an ultrasound device (DBM Sonic 1200, IGEA, Carpi, Italy). Mean AD-SoS values increased progressively from 3 to 21 y (males, 1845.9--2119.1 m/s, p < 0.0001; females, 1842.3--2098.8 m/s, p < 0.0001). They did not differ (p = NS) between sexes up to age 11, but females showed higher (p < 0.05 - p < 0.0001) AD-SoS values than males in age groups 12, 13, and 14 y. There was no difference (p = NS) of AD-SoS values between sexes in pubertal stages 1, 2, and 5, but females had higher mean AD-SoS values than males in stages 3 (p < 0.01) and 4 (p < 0.001). Independent predictors of AD-SoS were weight, body mass index, pubertal stage, and mean width of fingers in males, and age, pubertal stage, and mean width of fingers in females (p < 0.01 - p < 0.0001). However, 7.8% in males and 3.6% in females of the increment of AD-SoS values can be related to the finger anatomy alone. AD-SoS values probably reflect the architectural organization of growing bone or changes in bone elasticity. Increased bone density and size may be additional factors influencing AD-SOS: Measurement of AD-SoS at the hand phalanxes may be a simple, noninvasive, and radiation-free technique to assess bone quality in children.
- Subjects :
- Adult
Male
medicine.medical_specialty
Bone density
Adolescent
Urology
Fingers
Pubertal stage
Bone Density
Reference Values
Internal medicine
medicine
Humans
Young adult
Child
Ultrasonography
business.industry
Reproducibility of Results
Increased Bone Density
Phalanx
Hand
Diaphysis
Endocrinology
medicine.anatomical_structure
El Niño
Child, Preschool
Pediatrics, Perinatology and Child Health
Female
business
Body mass index
Subjects
Details
- ISSN :
- 00313998
- Volume :
- 49
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Pediatric research
- Accession number :
- edsair.doi.dedup.....848d0ce373de75bbae63ab0c534e0928