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Reconstructing Prehistoric African Population Structure
- Source :
- BASE-Bielefeld Academic Search Engine
- Publication Year :
- 2017
-
Abstract
- We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently divergent lineage that comprises the primary ancestry of the southern African San had a wider distribution in the past, contributing approximately two-thirds of the ancestry of Malawi hunter-gatherers ∼8,100-2,500 years ago and approximately one-third of the ancestry of Tanzanian hunter-gatherers ∼1,400 years ago. We document how the spread of farmers from western Africa involved complete replacement of local hunter-gatherers in some regions, and we track the spread of herders by showing that the population of a ∼3,100-year-old pastoralist from Tanzania contributed ancestry to people from northeastern to southern Africa, including a ∼1,200-year-old southern African pastoralist. The deepest diversifications of African lineages were complex, involving either repeated gene flow among geographically disparate groups or a lineage more deeply diverging than that of the San contributing more to some western African populations than to others. We finally leverage ancient genomes to document episodes of natural selection in southern African populations. PAPERCLIP.
- Subjects :
- 0301 basic medicine
Male
Genetics, Medical
Pastoralism
Population
Population genetics
Black People
Biology
General Biochemistry, Genetics and Molecular Biology
Article
Bone and Bones
Lineage (anthropology)
Prehistory
03 medical and health sciences
0302 clinical medicine
parasitic diseases
Humans
DNA, Ancient
education
Life Style
education.field_of_study
Fossils
Genome, Human
Population ecology
biology.organism_classification
030104 developmental biology
Ancient DNA
Tanzania
Genetics, Population
Africa
Ethnology
Female
030217 neurology & neurosurgery
Genome-Wide Association Study
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- BASE-Bielefeld Academic Search Engine
- Accession number :
- edsair.doi.dedup.....84b88fa853337e85e4912cd0a454cddf