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Percutaneous Transhepatic Cholangiography and Intraductal Radiofrequency Ablation Combined with Biliary Stent Placement for Malignant Biliary Obstruction
- Source :
- Journal of Vascular and Interventional Radiology. 26:715-721
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- To determine the safety and feasibility of percutaneous transhepatic cholangiography (PTC) and intraductal radiofrequency (RF) ablation combined with biliary stent placement for malignant biliary obstruction.Data from patients with unresectable malignant biliary obstruction who underwent PTC, intraductal RF ablation, and biliary stent placement (n = 12) or PTC and biliary stent placement only (control group; n = 14) were reviewed. Postoperative complications, jaundice remission, and stent patency were assessed.All procedures were successful. No severe complications (eg, biliary bleeding, perforation) occurred. Two experimental group patients developed cholangitis, which resolved with conservative treatment. The 1-week jaundice remission and 3-month stent patency rates were similar in both groups, but the 6-month stent patency rate was higher in the experimental group (P.05). In the experimental group, one death occurred as a result of gastrointestinal hemorrhage (unrelated to stent placement) by 3 months, and there were two cases of recurrent jaundice by 6 months. The latter two patients underwent repeat PTC, ablation, and stent placement. In the control group, one death occurred as a result of hepatic failure caused by progressive jaundice at 3 months, and another death resulted from disseminated intravascular coagulation caused by jaundice recurrence at 138 days after stent placement. In addition, seven patients developed jaundice recurrence (50-151 d after stent placement). PTC and repeat stent placement were performed in these patients.Percutaneous transhepatic cholangiography and intraductal RF ablation combined with biliary stent placement for malignant biliary obstruction is safe and feasible and effectively prolongs stent patency time.
- Subjects :
- Male
medicine.medical_specialty
Radiofrequency ablation
medicine.medical_treatment
Perforation (oil well)
Catheter ablation
Percutaneous transhepatic cholangiography
Stent patency
law.invention
Postoperative Complications
law
medicine
Humans
Radiology, Nuclear Medicine and imaging
cardiovascular diseases
Cholestasis
business.industry
Middle Aged
Jaundice
equipment and supplies
Ablation
Treatment Outcome
Bile Duct Neoplasms
Catheter Ablation
Biliary stent
Female
Stents
Radiology
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Cholangiography
Subjects
Details
- ISSN :
- 10510443
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Journal of Vascular and Interventional Radiology
- Accession number :
- edsair.doi.dedup.....84ce9455eec5a27d2692a940fcb31901