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Hepatic resection for non-colorectal, non-neuroendocrine, non-sarcoma metastasis: a single-centre experience
- Source :
- HPB. (4):286-292
- Publisher :
- International Hepato-Pancreato-Biliary Association. Published by Elsevier Ltd.
-
Abstract
- BackgroundThe aim of the present study was to analyse the outcome after hepatic resection for non-colorectal, non-neuroendocrine, non-sarcomatous (NCNNNS) metastatic tumours and to identify the factors predicting survival.MethodsAll patients who underwent hepatic resection for NCNNNS metastatic tumours between September 1996 and June 2009 were included. Patients' demographics, clinical and histopathological parameters, overall survival and the factors predicting survival were analysed.ResultsIn all, 65 patients underwent hepatic resection for metastasis. The most common site of a primary tumour was the kidney (24 patients). Fifteen patients had synchronous tumours. Fifty patients had major liver resections and 22 patients had bilobar disease. The median number of liver lesions resected was 1 and the median maximum diameter of the metastasis was 6cm. A R0 resection was performed in 51 patients. The 1-, 3- and 5-year overall survival from the time of metastasectomy was 72.9%, 47.9% and 25.6%, respectively, with a median survival of 19 months. The presence of a tumour of greater than 6cm (P= 0.048) and a positive resection margin (P= 0.04) were associated with poor survival.ConclusionHepatic resection for metastasis from NCNNNS tumours can offer acceptable long-term survival in selected patients. To offer a chance of a cure a R0 resection must be performed.
- Subjects :
- Adult
Male
Oncology
medicine.medical_specialty
Pathology
Time Factors
Hepatic resection
medicine.medical_treatment
hepatic resection
Kaplan-Meier Estimate
Risk Assessment
Disease-Free Survival
Metastasis
Neoplasms, Multiple Primary
Young Adult
Risk Factors
Internal medicine
medicine
Hepatectomy
Humans
metastasis
non-neuroendocrine
Young adult
Survival rate
Aged
Retrospective Studies
Hepatology
business.industry
non-colorectal
Liver Neoplasms
Gastroenterology
Retrospective cohort study
Original Articles
Middle Aged
medicine.disease
Survival Rate
Treatment Outcome
Non colorectal
England
Female
Sarcoma
business
Subjects
Details
- Language :
- English
- ISSN :
- 1365182X
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- HPB
- Accession number :
- edsair.doi.dedup.....8502306a9d770f59c39830afe44a2833
- Full Text :
- https://doi.org/10.1111/j.1477-2574.2010.00285.x