Back to Search Start Over

Comparison of coronary microcirculation in female nurses after day-time versus night-time shifts

Authors :
Kumiko Hirata
Shota Fukuda
Yasushi Kono
Minoru Yoshiyama
Reiko Miyahana
Kenichiro Otsuka
Satoshi Jissho
Tomoichiro Kubo
Junichi Yoshikawa
Kumiko Maeda
Haruyuki Taguchi
Takashi Akasaka
Koki Nakanishi
Kenichi Komukai
Kenei Shimada
Source :
The American journal of cardiology. 108(11)
Publication Year :
2011

Abstract

Nightshift work, which is known to cause mental stress and disrupt normal biological diurnal rhythms, leads to endothelial dysfunction resulting in increased risk for cardiovascular disease. This study aimed to investigate the acute effect of night-shift work on coronary microcirculation through assessment of coronary flow reserve (CFR) by transthoracic Doppler echocardiography. This study consisted of 36 women nurses who underwent transthoracic Doppler echocardiographic examinations after working a nightshift and on a regular day without previous nightshift work. Flow velocity in the distal portion of the left anterior descending coronary artery was measured at baseline and during adenosine infusion. CFR was calculated as the ratio of hyperemic to basal mean diastolic flow velocity. CFR after night work was lower than that on a regular workday (3.8 ± 0.6 vs 4.1 ± 0.6, p

Details

ISSN :
18791913
Volume :
108
Issue :
11
Database :
OpenAIRE
Journal :
The American journal of cardiology
Accession number :
edsair.doi.dedup.....85195f003b17a330ecff69936809f4a7