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Seroprevalence of antibodies to SARS-CoV-2 among blood donors in the early months of the pandemic in Saudi Arabia
- Source :
- International Journal of Infectious Diseases, Vol 104, Iss, Pp 452-457 (2021), International Journal of Infectious Diseases
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Highlights • Among blood donors in May 2020, te overall seroprevalence of anti-SARS-CoV-2 antibodies was 1.4% • Non-citizens had higher prevalence compared to citizens (odds ratio 13.6, p = 0.001). • There was geographic variation in seroprevalence of anti-SARS-CoV-2 antibodies within Saudi Arabia<br />Background Serologic testing provides better understanding of SARS-CoV-2 prevalence and its transmission. This study is the first investigation of the prevalence of antibodies to SARS-CoV-2 among blood donors in Saudi Arabia. Objective To estimate the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Saudi Arabia during the early phase of the current pandemic. Methods Serology results and epidemiological data were analyzed for 837 adult blood donors, with no confirmed SARS-CoV-2 infection, in Saudi Arabia from 20 to 25 May 2020. Seroprevalence was determined using electrochemical immunoassay for detecting anti-SARS-CoV-2 antibodies. Results The overall seroprevalence of anti-SARS-CoV-2 antibodies was 1.4% (12/837). Non-citizens had higher prevalence compared to citizens (odds ratio 13.6, p = 0.001). Having a secondary education as the highest level of education was also significantly associated with high seroprevalence compared to higher education (odds ratio 6.8, p = 0.005). The data showed that the highest seroprevalence was in Makkah (8.1%), Madinah (4.1% with an OR of 0.48 (95% CI: 0.12-1.94), Jeddah (2.3%; OR 0.27; 95%CI: 0.31-2.25), and Qassim (2.9 %, OR: 0.34; 95%CI: 0.04-2.89) and these were not statistically different from the seroprevalence in Makkah region. Conclusions At the early stage of the pandemic in Saudi Arabia, the seroprevalence of antibodies to SARS-CoV-2 among blood donors was low but was higher among non-citizens These findings showed that non-citizens and the less educated may be less attentive to preventive measures. Monitoring seroprevalence trend over time require repeated sampling.
- Subjects :
- Adult
Male
0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
Adolescent
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
education
030106 microbiology
Saudi Arabia
Seroprevalence
Antibodies, Viral
Blood donors
Article
lcsh:Infectious and parasitic diseases
Serology
Young Adult
03 medical and health sciences
0302 clinical medicine
Seroepidemiologic Studies
Environmental health
IgG antibody
Pandemic
Epidemiology
medicine
Humans
lcsh:RC109-216
030212 general & internal medicine
health care economics and organizations
Aged
Immunoassay
biology
SARS-CoV-2
Transmission (medicine)
business.industry
COVID-19
General Medicine
Middle Aged
Cross-Sectional Studies
Infectious Diseases
Immunoglobulin G
biology.protein
Female
Antibody
business
Subjects
Details
- ISSN :
- 12019712
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- International Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....85d959299d448da7ad95ec6e86dc8162