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Clinical usefulness of amikacin and doxycycline in the treatment of infection due to Mycobacterium fortuitum and Mycobacterium chelonei
- Source :
- Reviews of infectious diseases. 3(5)
- Publication Year :
- 1981
-
Abstract
- The antimicrobial agents amikacin and doxycycline, which are not conventionally considered for use in treatment of mycobacterial infections, inhibit growth of Mycobacterium fortuitum and Mycobacterium chelonei in vitro. Ten patients were treated with these drugs alone or in combination with some surgical procedure. Seven of the 10 patients were definitely cured by the therapy. Only one definite treatment failure occurred. Patients with infections due to M. fortuitum or M. chelonei that are susceptible in vitro to these drugs appear to benefit from chemotherapy.
- Subjects :
- Microbiology (medical)
Adult
Male
medicine.medical_treatment
Mycobacterium chelonei
Mycobacterium chelonae
Mycobacterium Infections, Nontuberculous
Microbiology
Kanamycin
medicine
Humans
Amikacin
Aged
Doxycycline
Chemotherapy
Mycobacterium Infections
biology
business.industry
Nontuberculous Mycobacteria
biochemical phenomena, metabolism, and nutrition
Middle Aged
bacterial infections and mycoses
biology.organism_classification
Antimicrobial
Chemotherapy regimen
Infectious Diseases
Child, Preschool
Mycobacterium fortuitum
Female
business
medicine.drug
Subjects
Details
- ISSN :
- 01620886
- Volume :
- 3
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Reviews of infectious diseases
- Accession number :
- edsair.doi.dedup.....8630a9e1933f53f2c93dd5c9571c3eab