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EAACI guideline: Anaphylaxis (2021 update)
- Source :
- Allergy, Allergy, Wiley, 2021, ⟨10.1111/all.15032⟩, Allergy: European Journal of Allergy and Clinical Immunology, 77(2), 357-377. Wiley-Blackwell, Muraro, A, Worm, M, Alviani, C, Cardona, V, DunnGalvin, A, Garvey, L H, Riggioni, C, Silva, D D, Angier, E, Arasi, S, Bellou, A, Beyer, K, Bijlhout, D, Bilò, M B, Bindslev-Jensen, C, Brockow, K, Fernandez-Rivas, M, Halken, S, Jensen, B, Khaleva, E, Michaelis, L J, Elberink, H N G O, Regent, L, Sanchez, A, Vlieg-Boerstra, B J & Roberts, G 2022, ' EAACI guideline : Anaphylaxis (2021 update) ', Allergy, vol. 77, no. 2, pp. 357-377 . https://doi.org/10.1111/all.15032, Muraro, A, Worm, M, Alviani, C, Cardona, V, DunnGalvin, A, Garvey, L H, Riggioni, C, de Silva, D, Angier, E, Arasi, S, Bellou, A, Beyer, K, Bijlhout, D, Bilò, M B, Bindslev-Jensen, C, Brockow, K, Fernandez-Rivas, M, Halken, S, Jensen, B, Khaleva, E, Michaelis, L J, Oude Elberink, H N G, Regent, L, Sanchez, A, Vlieg-Boerstra, B J, Roberts, G & European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group 2022, ' EAACI guidelines : Anaphylaxis (2021 update) ', Allergy: European Journal of Allergy and Clinical Immunology, vol. 77, no. 2, pp. 357-377 . https://doi.org/10.1111/all.15032, Allergy, 2021, ⟨10.1111/all.15032⟩
- Publication Year :
- 2021
-
Abstract
- Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognise and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritise clinical trials with the potential to improve the management of patients at risk of anaphylaxis. Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognize and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first-line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritize clinical trials with the potential to improve the management of patients at risk of anaphylaxis.
- Subjects :
- Allergy
Epinephrine
First line
[SDV]Life Sciences [q-bio]
Immunology
Guidelines
03 medical and health sciences
0302 clinical medicine
children
Autoinjector
adults
anaphylaxis
Humans
Immunology and Allergy
Medicine
Adults
guidelines
Anaphylaxis
Children
030304 developmental biology
0303 health sciences
Health professionals
business.industry
Guideline
medicine.disease
3. Good health
Clinical trial
030228 respiratory system
Tryptases
Medical emergency
business
Blood sampling
Subjects
Details
- Language :
- English
- ISSN :
- 01054538 and 13989995
- Database :
- OpenAIRE
- Journal :
- Allergy, Allergy, Wiley, 2021, ⟨10.1111/all.15032⟩, Allergy: European Journal of Allergy and Clinical Immunology, 77(2), 357-377. Wiley-Blackwell, Muraro, A, Worm, M, Alviani, C, Cardona, V, DunnGalvin, A, Garvey, L H, Riggioni, C, Silva, D D, Angier, E, Arasi, S, Bellou, A, Beyer, K, Bijlhout, D, Bilò, M B, Bindslev-Jensen, C, Brockow, K, Fernandez-Rivas, M, Halken, S, Jensen, B, Khaleva, E, Michaelis, L J, Elberink, H N G O, Regent, L, Sanchez, A, Vlieg-Boerstra, B J & Roberts, G 2022, ' EAACI guideline : Anaphylaxis (2021 update) ', Allergy, vol. 77, no. 2, pp. 357-377 . https://doi.org/10.1111/all.15032, Muraro, A, Worm, M, Alviani, C, Cardona, V, DunnGalvin, A, Garvey, L H, Riggioni, C, de Silva, D, Angier, E, Arasi, S, Bellou, A, Beyer, K, Bijlhout, D, Bilò, M B, Bindslev-Jensen, C, Brockow, K, Fernandez-Rivas, M, Halken, S, Jensen, B, Khaleva, E, Michaelis, L J, Oude Elberink, H N G, Regent, L, Sanchez, A, Vlieg-Boerstra, B J, Roberts, G & European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group 2022, ' EAACI guidelines : Anaphylaxis (2021 update) ', Allergy: European Journal of Allergy and Clinical Immunology, vol. 77, no. 2, pp. 357-377 . https://doi.org/10.1111/all.15032, Allergy, 2021, ⟨10.1111/all.15032⟩
- Accession number :
- edsair.doi.dedup.....86eb519f8173dd1e389dbcc5ceee3d04