Back to Search
Start Over
The Effects of Inositol Metabolism in Pregnant Women on Offspring in the North and South of China
- Source :
- Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
- Publication Year :
- 2020
- Publisher :
- International Scientific Literature, Inc., 2020.
-
Abstract
- BACKGROUND Inositol is an essential nutrient for cell growth, survival and embryonic development. Myo-inositol is the predominant form in natural. To investigate the correlation between inositol metabolism and embryonic development, we assessed the metabolic characteristics of myo-inositol, phosphatidylinositol 4,5-bisphosphate (PI(4,5)P₂) and phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P₃) of pregnant women in the North China (Yangquan and Weihai) and South China (Nanchang and Haikou) China. MATERIAL AND METHODS All data were collected by face-to-face interview during pregnant women health visits using a questionnaire. Plasma levels of myo-inositol, PI(4,5)P₂ and PI(3,4,5)P₃ from 89 randomly collected pregnant women were detected by gas chromatography-mass spectrometry and enzyme linked immunosorbent assay. RESULTS A total of 400 pregnant women were included in this survey. The plasma levels of myo-inositol and PI(4,5)P₂ in the North China group of pregnant women were significantly higher than that in the South China group (P
- Subjects :
- Adult
Phosphatidylinositol 4,5-Diphosphate
China
Offspring
Birth weight
030204 cardiovascular system & hematology
Congenital Abnormalities
Andrology
Fetal Development
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Phosphatidylinositol Phosphates
Clinical Research
Pregnancy
medicine
Humans
Inositol
Fetus
Geography
Incidence (epidemiology)
Inositol Metabolism
Incidence
Body Weight
Infant, Newborn
General Medicine
medicine.disease
chemistry
030220 oncology & carcinogenesis
Female
Pregnant Women
Subjects
Details
- Language :
- English
- ISSN :
- 16433750 and 12341010
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
- Accession number :
- edsair.doi.dedup.....88064b575cde740d7775c6c5cb30ff51