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Histoplanimetrical Study on the Relationship between the Cell Kinetics of Villous Columnar Epithelial Cells and the Proliferation of Indigenous Bacteria in Rat Small Intestine
- Source :
- Journal of Veterinary Medical Science. 71:463-470
- Publication Year :
- 2009
- Publisher :
- Japanese Society of Veterinary Science, 2009.
-
Abstract
- The relationship between the kinetics of villous columnar epithelial cells and the expansion of colonies of indigenous bacteria from the narrow apical portions of intestinal villi was immunohistochemically and histoplanimetrically investigated in the small intestine of bromodeoxyuridine administred Wistar rats. As a result, the lifespan of villous columnar epithelial cells was slightly shorter in the distal ileum than in other portions of small intestine, accompanying the minimum height of the intestinal villi of the distal ileum in the small intestine. The migration speed of villous columnar epithelial cells was significantly decreased toward the distal small intestine. The migration speed in the distal ileum was about one-fourth of that in the duodenum. The migration speed of the villous columnar epithelial cells was greater and their lifespans were shorter in the sites with wide expansion of the indigenous bacterial colony from the narrow apical portions of the intestinal villi than that in sites with no or less expansion. Additionally, the expansion of the indigenous bacterial colony from narrow villous apices also immediately shortened the heights of the intestinal villi. These findings suggest that the migration speed of villous columnar epithelial cells might contribute to the regulation of the settlement of bacteria at the villous apices and the inevitable proliferation of indigenous bacteria at the intervillous spaces in the rat small intestine.
- Subjects :
- Male
Ileum
Biology
digestive system
Rat Small Intestine
chemistry.chemical_compound
Intestine, Small
medicine
Animals
Intestinal Mucosa
Rats, Wistar
Gastrointestinal tract
General Veterinary
Epithelial Cells
Anatomy
Immunohistochemistry
Molecular biology
Epithelium
Small intestine
Rats
Kinetics
medicine.anatomical_structure
chemistry
Apoptosis
embryonic structures
Duodenum
Bromodeoxyuridine
Subjects
Details
- ISSN :
- 13477439 and 09167250
- Volume :
- 71
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Medical Science
- Accession number :
- edsair.doi.dedup.....881e58dfd1dab852aec659c6918f1c9c