Back to Search
Start Over
Prevalence of Chagas Disease among Solid Organ-Transplanted Patients in a Nonendemic Country
- Source :
- The American journal of tropical medicine and hygiene. 98(3)
- Publication Year :
- 2018
-
Abstract
- Reactivation of Chagas disease in the chronic phase may occur after solid organ transplantation, which may result in high parasitemia and severe clinical manifestations such as myocarditis and meningoencephalitis. The aim of the present study is to describe the prevalence of Chagas disease among solid organ–transplanted patients in a tertiary hospital from a nonendemic country. A cross-sectional study was performed at Vall d’Hebron University Hospital (Barcelona, Spain) from April to September 2016. Chagas disease screening was performed through serological tests in adult patients coming from endemic areas that had received solid organ transplantation and were being controlled in our hospital during the study period. Overall, 42 patients were included, 20 (47.6%) were male and median age was 50.5 (23–73) years. Transplanted organs were as follows: 18 kidneys, 17 lungs, and 7 livers. Three patients had Chagas disease, corresponding to a prevalence among this group of solid organ–transplanted patients of 7.1%. All three patients were born in Bolivia, had been diagnosed with Chagas disease and received specific treatment before the organ transplantation. We highly recommend providing screening tests for Chagas disease in patients with or candidates for solid organ transplantation coming from endemic areas, early treatment with benznidazole, and close follow-up to prevent clinical reactivations.
- Subjects :
- Chagas disease
Adult
Male
medicine.medical_specialty
Pediatrics
Myocarditis
Parasitemia
030230 surgery
Organ transplantation
Serology
03 medical and health sciences
0302 clinical medicine
Virology
Prevalence
Medicine
Humans
Chagas Disease
030212 general & internal medicine
Aged
business.industry
Meningoencephalitis
Organ Transplantation
Articles
Middle Aged
medicine.disease
Infectious Diseases
Cross-Sectional Studies
Benznidazole
Parasitology
Female
Solid organ
business
medicine.drug
Subjects
Details
- ISSN :
- 14761645
- Volume :
- 98
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The American journal of tropical medicine and hygiene
- Accession number :
- edsair.doi.dedup.....889b2e266868e96d170ea917e3e2bc9a