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Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015
- Source :
- Cancers, Volume 11, Issue 8, Cancers, Vol 11, Iss 8, p 1180 (2019)
- Publication Year :
- 2019
-
Abstract
- The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in the central Japanese main island, with a population of around 22.66 million individuals. This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006&ndash<br />2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC.
- Subjects :
- 0301 basic medicine
Cancer Research
medicine.medical_specialty
Population
Central region
lcsh:RC254-282
survival
Article
Serology
03 medical and health sciences
0302 clinical medicine
Japan
Internal medicine
Epidemiology
medicine
Overall survival
otorhinolaryngologic diseases
education
education.field_of_study
nasopharyngeal carcinoma (NPC)
business.industry
Incidence (epidemiology)
Medical record
medicine.disease
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
stomatognathic diseases
030104 developmental biology
Oncology
Nasopharyngeal carcinoma
030220 oncology & carcinogenesis
incidence
business
Subjects
Details
- ISSN :
- 20726694
- Volume :
- 11
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Cancers
- Accession number :
- edsair.doi.dedup.....8934f14c60097f7814d50d001ababa15