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Self-Report Daily Life Activity as a Prognostic Marker of Idiopathic Pulmonary Fibrosis
- Source :
- Respiration; international review of thoracic diseases. 90(6)
- Publication Year :
- 2015
-
Abstract
- Background: Idiopathic pulmonary fibrosis (IPF) is a progressive disease, leading to substantial physical impairment. The distance walked in 6 min (6MWD) is a measure of exercise tolerance and is of prognostic relevance in IPF. While 6MWD is a punctual measurement which may not be representative, self-reported daily life activity may represent the patients' functional capacity more globally even in less severe affected patients. Objectives: We evaluated and characterized a simple classification system based on the patients' self-reported daily activity and analyzed if this would add significantly to the prognostic information of the 6MWD alone in IPF patients. Methods: Daily life activity was assessed in IPF (n = 156) patients with standardized questions and categorized in activity classes (AC I-IV), comprising the less severe impaired in AC I and II. The 6MWD was also assessed. Results: ACs were related to the lung functional impairment and inversely correlated to the 6MWD. Thirty-two patients were in AC I/II, 98 in AC III and 26 patients in AC IV. Thirty-seven (23.7%) patients died during a median follow-up of 14.9 months, comprising 1 patient in AC I/II. In addition, a 6MWD 470 m identified a subgroup of patients with favorable outcome. Conclusions: AC is a novel scoring system which can easily be obtained and correlates with lung functional and physical impairments as well as mortality. Moreover, AC adds prognostic information to the 6MWD.
- Subjects :
- Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
Pathology
Gastroenterology
Severity of Illness Index
Life activity
Idiopathic pulmonary fibrosis
Internal medicine
Germany
Severity of illness
Activities of Daily Living
medicine
Humans
Prospective Studies
Prospective cohort study
Self report
Idiopathic interstitial pneumonia
business.industry
Disease progression
food and beverages
respiratory system
Middle Aged
medicine.disease
Prognosis
Idiopathic Pulmonary Fibrosis
respiratory tract diseases
Respiratory Function Tests
Disease Progression
Exercise Test
Female
Self Report
business
Progressive disease
Follow-Up Studies
Subjects
Details
- ISSN :
- 14230356
- Volume :
- 90
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Respiration; international review of thoracic diseases
- Accession number :
- edsair.doi.dedup.....895aabb7470d32022ccf6f6cade75f64