Low Hemoglobin Levels and the Onset of Cognitive Impairment in Older People: The PRO.V.A. Study

Authors :: Francesco Bolzetta
Stefania Maggi
Gaetano Crepaldi
Caterina Trevisan
Nicola Veronese
Egle Perissinotto
S Zambon
Giuseppe Sergi
Leonardo Sartori
Enzo Manzato
Marina De Rui
Estella Musacchio
Trevisan, C.
Veronese, N.
Bolzetta, F.
De Rui, M.
Maggi, S.
Zambon, S.
Musacchio, E.
Sartori, L.
Perissinotto, E.
Crepaldi, G.
Manzato, E.
Sergi, G.
Publication Year :: 2016
Publisher :: Mary Ann Liebert Inc. Publishers, 2016.
Abstract: Low hemoglobin (Hb) levels are attracting interest as a risk factor for cognitive impairment, but with contrasting evidence emerging from the current literature. The aim of our work was to investigate the relationship between baseline serum Hb levels and the incidence of cognitive impairment in older people over a follow-up of 4.4 years. Our study considered a sample of 1227 elderly subjects cognitively intact at baseline, enrolled under the Progetto Veneto Anziani (Pro.V.A.) among 3099 screened subjects. For all participants, we measured serum Hb levels on blood samples; incident cognitive impairment was defined as a Mini Mental State Examination (MMSE) score

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