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Effects of low-level laser therapy on autogenous bone graft stabilized with a new heterologous fibrin sealant
- Source :
- Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP, Scopus, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP
- Publication Year :
- 2016
-
Abstract
- Made available in DSpace on 2018-12-11T17:04:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-01 Autogenous bone grafts are used to repair bone defects, and the stabilization is needed for bone regeneration. Laser photobiomodulation is a modality of treatment in clinical practice for tissue regeneration, and it has therapeutic effects as an anti-inflammatory, analgesic and modulating cellular activity. The aim of the present study was to evaluate the effects of low-level laser therapy (LLLT) on an autogenous bone graft integration process stabilized with a new heterologous fibrin sealant. Forty rats were divided into two groups: Autogenous Fibrin Graft (AFG, n = 20), in which a 5 mm dome osteotomy was conducted in the right parietal bone and the graft was adhered to the left side using fibrin sealant; and Autogenous Fibrin Graft Laser (AFGL, n = 20), which was subjected to the same procedures as AFG with the addition of LLLT. The treatment was performed immediately following surgery and then three times a week until euthanasia, using an 830 nm laser (30 mW, 6 J/cm2, 0.116 cm2, 258.6 mW/cm2, 2.9 J). Five animals from each group were euthanized at 10, 20, 30 and 40 days postoperative, and the samples were submitted to histomorphological and histomorphometric analysis. Partial bone regeneration occurred, with new bone tissue integrating the graft to the recipient bed and small areas of connective tissue. Comparative analysis of the groups at the same intervals revealed minor interfaces in group AFGL, with statistically significant differences (p
- Subjects :
- Male
Fibrin sealant
medicine.medical_specialty
Bone Regeneration
medicine.medical_treatment
Biophysics
Heterologous
Connective tissue
Fibrin Tissue Adhesive
LASER NÃO CIRÚRGICO
Bone tissue
Fibrin
Bone and Bones
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Laser therapy
medicine
Bone graft
Animals
Radiology, Nuclear Medicine and imaging
Low-Level Light Therapy
Rats, Wistar
Bone regeneration
Low level laser therapy
Radiation
Bone Transplantation
Radiological and Ultrasound Technology
biology
business.industry
Sealant
Therapeutic effect
030206 dentistry
Surgery
Rats
medicine.anatomical_structure
biology.protein
Bone Diseases
Osseous defects
business
Subjects
Details
- ISSN :
- 18732682
- Volume :
- 162
- Database :
- OpenAIRE
- Journal :
- Journal of photochemistry and photobiology. B, Biology
- Accession number :
- edsair.doi.dedup.....89b6d7d5d7ba8e44e9abea9219251b55