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Cellular stress responses to chronic heat shock and shell damage in temperate Mya truncata
- Source :
- Cell Stress & Chaperones
- Publication Year :
- 2018
- Publisher :
- Springer Netherlands, 2018.
-
Abstract
- VAS was funded by a NERC DTG studentship (Project Reference: NE/J500173/1) to the British Antarctic Survey. MSC and LSP were financed by NERC core funding to the British Antarctic Survey. Acclimation, via phenotypic flexibility, is a potential means for a fast response to climate change. Understanding the molecular mechanisms underpinning phenotypic flexibility can provide a fine-scale cellular understanding of how organisms acclimate. In the last 30 years, Mya truncata populations around the UK have faced an average increase in sea surface temperature of 0.7 °C and further warming of between 1.5 and 4 °C, in all marine regions adjacent to the UK, is predicted by the end of the century. Hence, data are required on the ability of M. truncata to acclimate to physiological stresses, and most notably, chronic increases in temperature. Animals in the present study were exposed to chronic heat-stress for 2 months prior to shell damage and subsequently, only 3, out of 20 damaged individuals, were able to repair their shells within 2 weeks. Differentially expressed genes (between control and damaged animals) were functionally enriched with processes relating to cellular stress, the immune response and biomineralisation. Comparative transcriptomics highlighted genes, and more broadly molecular mechanisms, that are likely to be pivotal in this lack of acclimation. This study demonstrates that discovery-led transcriptomic profiling of animals during stress-response experiments can shed light on the complexity of biological processes and changes within organisms that can be more difficult to detect at higher levels of biological organisation. Publisher PDF
- Subjects :
- 0106 biological sciences
0301 basic medicine
Mya truncata
QH301 Biology
Acclimatization
Immunology
Mya
010603 evolutionary biology
01 natural sciences
Biochemistry
Transcriptome
QH301
03 medical and health sciences
Animal Shells
Heat shock protein
Protein Interaction Mapping
SDG 13 - Climate Action
Temperate climate
Animals
QR180 Immunology
SDG 14 - Life Below Water
14. Life underwater
Heat shock
Transcriptomics
Gene
Heat-Shock Proteins
Original Paper
biology
Heat shock proteins
Bivalve
Biomineralisation
DAS
Cell Biology
biology.organism_classification
Phenotype
030104 developmental biology
13. Climate action
Evolutionary biology
QR180
Mollusc
Reactive oxygen species
Heat-Shock Response
Subjects
Details
- Language :
- English
- ISSN :
- 14661268 and 13558145
- Volume :
- 23
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Cell Stress & Chaperones
- Accession number :
- edsair.doi.dedup.....89eab29dab589681853d34f64570a5b9