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Consumption of antibiotics in the community, European Union/European Economic Area, 1997-2017
- Source :
- The journal of antimicrobial chemotherapy, Journal of Antimicrobial Chemotherapy, 76, 12 Suppl 2, pp. ii7-ii13, Journal of Antimicrobial Chemotherapy, 76, ii7-ii13, Journal of Antimicrobial Chemotherapy
- Publication Year :
- 2021
-
Abstract
- Objectives Data on antibiotic consumption in the community were collected from 30 EU/EEA countries over two decades. This article reviews temporal trends, seasonal variation, presence of change-points and changes in the composition of the main antibiotic groups. Methods For the period 1997–2017, data on consumption of antibiotics, i.e. antibacterials for systemic use (ATC group J01), in the community, aggregated at the level of the active substance, were collected using the WHO ATC/DDD methodology (ATC/DDD index 2019). Consumption was expressed in DDD per 1000 inhabitants per day and in packages per 1000 inhabitants per day. Antibiotic consumption was analysed based on ATC-3 groups, and presented as trends, seasonal variation, presence of change-points and compositional changes. Results In 2017, antibiotic consumption in the community expressed in DDD per 1000 inhabitants per day varied by a factor 3.6 between countries with the highest (Greece) and the lowest (the Netherlands) consumption. Antibiotic consumption in the EU/EEA did not change significantly over time. Antibiotic consumption showed a significant seasonal variation, which decreased over time. The number of DDD per package significantly increased over time. The proportional consumption of sulphonamides and trimethoprim (J01E) relative to other groups significantly decreased over time, while the proportional consumption of other antibacterials (J01X) relative to other groups significantly increased over time. Conclusions Overall, antibiotic consumption in the community in the EU/EEA did not change during 1997–2017, while seasonal variation consistently decreased over time. The number of DDD per package increased during 1997–2017.
- Subjects :
- 0301 basic medicine
Pharmacology
Microbiology (medical)
Pharmacology. Therapy
030106 microbiology
Bacterial Infections
Drug Utilization
Trimethoprim
Anti-Bacterial Agents
03 medical and health sciences
AcademicSubjects/MED00290
lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]
0302 clinical medicine
Infectious Diseases
Supplement Papers
AcademicSubjects/MED00740
Humans
Pharmacology (medical)
Human medicine
030212 general & internal medicine
European Union
AcademicSubjects/MED00230
Biology
Subjects
Details
- ISSN :
- 03057453
- Database :
- OpenAIRE
- Journal :
- The journal of antimicrobial chemotherapy, Journal of Antimicrobial Chemotherapy, 76, 12 Suppl 2, pp. ii7-ii13, Journal of Antimicrobial Chemotherapy, 76, ii7-ii13, Journal of Antimicrobial Chemotherapy
- Accession number :
- edsair.doi.dedup.....89ef015aae61dede20a482becf5ae298