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Effects of Unsweetened Preloads and Preloads Sweetened with Caloric or Low-/No-Calorie Sweeteners on Subsequent Energy Intakes: A Systematic Review and Meta-Analysis of Controlled Human Intervention Studies
- Source :
- Advances in Nutrition
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Effects of isocaloric (sweetness differences but constant calories) preloads and isosweet (caloric differences but constant sweetness) preloads, as well as preloads that were neither isosweet nor isocaloric (sweetness and caloric differences) on subsequent ad libitum meal and total (preload + ad libitum) energy intakes were investigated. Thirty-five crossover studies were eligible for inclusion, representing 116 comparisons (41, isocaloric; 41, isosweet; and 34, neither isosweet nor isocaloric). References of existing reviews and literature from 4 databases were searched. The calculated raw mean differences in ad libitum and total energy intakes were pooled in meta-analyses using a random-effects model and the inverse of the variance as the weighting factor. Energy intakes at an ad libitum meal were significantly lower for low-/no-calorie sweetener (LNCS)–sweetened compared with unsweetened preloads in the isocaloric comparison (−55.5 kcal; 95% CI: −82.9, −28.0 kcal; P
- Subjects :
- ad libitum
food intake
Calorie
Medicine (miscellaneous)
postprandial
Review
Beverages
Eating
AcademicSubjects/MED00060
Animal science
Humans
Medicine
Meals
Meal
Nutrition and Dietetics
business.industry
digestive, oral, and skin physiology
caloric sweetener
acute
food and beverages
Caloric theory
noncaloric sweetener
Sweetness
Preload
Postprandial
Sweetening Agents
Taste
Meta-analysis
preload
short-term
energy intake
Energy intakes
low-calorie sweetener
business
human activities
Food Science
Subjects
Details
- ISSN :
- 21618313
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Advances in Nutrition
- Accession number :
- edsair.doi.dedup.....89f41d192da1909ae2f43ee3063e8e93