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Role of Glucagon and Adrenergic Receptors in Thyrocalcitonin Release in the Dog
- Source :
- Endocrinology. 88:1337-1340
- Publication Year :
- 1971
- Publisher :
- The Endocrine Society, 1971.
-
Abstract
- Data obtained in the dog during thyroid perfusion support the hypothesis that glucagon and epinephrine stimulate thyrocalcitonin release via adenyl cyclase activation and consequently by the intracellular level of cyclic adenosine monophosphate. The studies also suggest that agonists acting at alpha adrenergic loci may lead to a reduction in cyclic adenosine monophosphate in the parafollicular thyroid cells. (Endocrinology 88: 1337, 1971)
- Subjects :
- Calcitonin
endocrine system
medicine.medical_specialty
Sympathetic Nervous System
Epinephrine
Sensory Receptor Cells
Adrenergic receptor
Cyclase
Glucagon
chemistry.chemical_compound
Dogs
Endocrinology
Theophylline
Internal medicine
Cyclic AMP
medicine
Animals
Cyclic adenosine monophosphate
Phentolamine
Hypocalcemia
Adenine Nucleotides
Chemistry
Thyroid
Isoproterenol
Propranolol
Stimulation, Chemical
Rats
medicine.anatomical_structure
Female
Intracellular
Adenylyl Cyclases
medicine.drug
Subjects
Details
- ISSN :
- 19457170 and 00137227
- Volume :
- 88
- Database :
- OpenAIRE
- Journal :
- Endocrinology
- Accession number :
- edsair.doi.dedup.....8a23833b1956ffadcc748029acc63db5