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Mesenchymal Tumors of the Mediastinum: An Update on Diagnostic Approach

Authors :
Jae Y. Ro
Joon Hyuk Choi
Source :
Advances in Anatomic Pathology. 28:351-381
Publication Year :
2021
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2021.

Abstract

Mesenchymal tumors of the mediastinum are a heterogenous group of rare tumors with divergent lineages. Mediastinal mesenchymal tumors are diagnostically challenging due to their diversity and morphologic overlap with nonmesenchymal lesions arising in the mediastinum. Accurate histologic diagnosis is critical for appropriate patient management and prognostication. Many mediastinal mesenchymal tumors affect distinct age groups or occur at specific mediastinal compartments. Neurogenic tumors, liposarcoma, solitary fibrous tumor, and synovial sarcoma are common mesenchymal tumors in the mediastinum. Herein, we provide an update on the diagnostic approach to mediastinal mesenchymal tumors and a review of the histologic features and differential diagnosis of common benign and malignant mesenchymal tumors of the mediastinum.

Details

ISSN :
10724109
Volume :
28
Database :
OpenAIRE
Journal :
Advances in Anatomic Pathology
Accession number :
edsair.doi.dedup.....8a2fb5d9e4f8d387f4c3cf5d1eb3ff3b
Full Text :
https://doi.org/10.1097/pap.0000000000000306