Back to Search Start Over

Prognostic significance of preoperative circulating FAR and FCI scores in patients with ovarian cancer

Authors :
Ling Cheng
Yanjun Shen
Xiaoyan Ding
Yongfen Ding
Juan Lai
Huige Wang
Source :
Clinica Chimica Acta. 509:252-257
Publication Year :
2020
Publisher :
Elsevier BV, 2020.

Abstract

Background Ovarian malignancy is among the most common lethal cancers in gynaecology. It has been considered that nutrition status and inflammation are two essential factors associated with the poor survival rates of patients suffering from multiple tumours. Methods This research included 174 subjects who suffered from FIGO stage I-IV OC and underwent surgeries between May 2008 and March 2013. Results The results showed that FAR, T3–T4 depth, high CA125, stage III-IV and metastasis were highly associated with low overall survival rates. Moreover, higher FCI was markedly correlated with decreased survival in patients with OC. Conclusions The combination of FAR and CA125 could be a new non-invasive marker in blood and probably assist physicians in evaluating the prognosis of patients.

Details

ISSN :
00098981
Volume :
509
Database :
OpenAIRE
Journal :
Clinica Chimica Acta
Accession number :
edsair.doi.dedup.....8a501738c337b657561381e168c79c6a
Full Text :
https://doi.org/10.1016/j.cca.2020.06.034