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Prognostic significance of preoperative circulating FAR and FCI scores in patients with ovarian cancer
- Source :
- Clinica Chimica Acta. 509:252-257
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Background Ovarian malignancy is among the most common lethal cancers in gynaecology. It has been considered that nutrition status and inflammation are two essential factors associated with the poor survival rates of patients suffering from multiple tumours. Methods This research included 174 subjects who suffered from FIGO stage I-IV OC and underwent surgeries between May 2008 and March 2013. Results The results showed that FAR, T3–T4 depth, high CA125, stage III-IV and metastasis were highly associated with low overall survival rates. Moreover, higher FCI was markedly correlated with decreased survival in patients with OC. Conclusions The combination of FAR and CA125 could be a new non-invasive marker in blood and probably assist physicians in evaluating the prognosis of patients.
- Subjects :
- 0301 basic medicine
Oncology
medicine.medical_specialty
Multiple tumours
Clinical Biochemistry
Carcinoma, Ovarian Epithelial
Biochemistry
Metastasis
03 medical and health sciences
0302 clinical medicine
Internal medicine
Biomarkers, Tumor
medicine
Overall survival
Humans
In patient
Stage (cooking)
Ovarian malignancy
Neoplasm Staging
Ovarian Neoplasms
business.industry
Biochemistry (medical)
General Medicine
Prognosis
medicine.disease
030104 developmental biology
CA-125 Antigen
030220 oncology & carcinogenesis
Female
Ovarian cancer
business
Subjects
Details
- ISSN :
- 00098981
- Volume :
- 509
- Database :
- OpenAIRE
- Journal :
- Clinica Chimica Acta
- Accession number :
- edsair.doi.dedup.....8a501738c337b657561381e168c79c6a
- Full Text :
- https://doi.org/10.1016/j.cca.2020.06.034