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Survival and immune response of drones of a Nosemosis tolerant honey bee strain towards N. ceranae infections
- Source :
- Journal of Invertebrate Pathology, Journal of Invertebrate Pathology, Elsevier, 2012, 109, pp.297-302. ⟨10.1016/j.jip.2012.01.004⟩, Huanga, Q, Kryger, P, Le Conte, Y & Moritz, R F A 2012, ' Survival and immune response of drones of a Nosemosis tolerant honey bee strain towards N. ceranae infections ', Journal of Invertebrate Pathology, vol. 109, no. 3, pp. 297–302 . https://doi.org/10.1016/j.jip.2012.01.004
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- International audience; Honey bee colonies (Apis mellifera) have been selected for low level of Nosema in Denmark over decades and Nosema is now rarely found in bee colonies from these breeding lines. We compared the immune response of a selected and an unselected honey bee lineage, taking advantage of the haploid males to study its potential impact on the tolerance toward Nosema ceranae, a novel introduced microsporidian pathogen. After artificial infections of the N. Ceranae spores, the lineage selected for Nosema tolerance showed a higher N. ceranae spore load, a lower mortality and an up-regulated immune response. The differences in the response of the innate immune system between the selected and unselected lineage were strongest at day six post infection. In particular genes of the Toll pathway were up-regulated in the selected strain, probably is the main immune pathway involved in N. ceranae infection response. After decades of selective breeding for Nosema tolerance in the Danish strain, it appears these bees are tolerant to N. ceranae infections
- Subjects :
- 0106 biological sciences
Male
NOSEMA CERANAE
MICROSPORIDIE
HYMENOPTERA
Selective breeding
Real-Time Polymerase Chain Reaction
01 natural sciences
Microbiology
03 medical and health sciences
Immune system
Nosema
Botany
Microsporidiosis
Animals
Pathogen
Ecology, Evolution, Behavior and Systematics
abeille domestique
030304 developmental biology
IMMUNITE
0303 health sciences
Innate immune system
biology
Reverse Transcriptase Polymerase Chain Reaction
Gene Expression Profiling
fungi
APIS MELLIFERA
Honey bee
Bees
biology.organism_classification
Nosema ceranae
Spore
[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology
010602 entomology
behavior and behavior mechanisms
MALE HAPLOIDE
NOSEMOSE
APIDAE
Signal Transduction
Subjects
Details
- Language :
- English
- ISSN :
- 00222011 and 10960805
- Database :
- OpenAIRE
- Journal :
- Journal of Invertebrate Pathology, Journal of Invertebrate Pathology, Elsevier, 2012, 109, pp.297-302. ⟨10.1016/j.jip.2012.01.004⟩, Huanga, Q, Kryger, P, Le Conte, Y & Moritz, R F A 2012, ' Survival and immune response of drones of a Nosemosis tolerant honey bee strain towards N. ceranae infections ', Journal of Invertebrate Pathology, vol. 109, no. 3, pp. 297–302 . https://doi.org/10.1016/j.jip.2012.01.004
- Accession number :
- edsair.doi.dedup.....8a64501323e209099f2f63bd76df59be
- Full Text :
- https://doi.org/10.1016/j.jip.2012.01.004⟩