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Search for Antifungal Compounds from the Wood of Durable Tropical Trees

Authors :
Maria do Rosário Rodrigues Silva
Alice M. S. Rodrigues
Laila S. Espindola
Phellipe N. E. T. Theodoro
Didier Stien
Jacques Beauchêne
Véronique Eparvier
Charlie Basset
Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM)
PIERRE FABRE-EDF (EDF)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Observatoire océanologique de Banyuls (OOB)
Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
Ecologie des forêts de Guyane (ECOFOG)
Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université des Antilles et de la Guyane (UAG)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS)
Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM)
Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)
Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)
Universidade de Brasilia [Brasília] (UnB)
Universidade Federal de Goiás [Goiânia] (UFG)
Source :
Journal of Natural Products, Journal of Natural Products, American Chemical Society, 2010, 73 (10), pp.1706-1707. ⟨10.1021/np1001412⟩, Journal of Asian Natural Products Research, Journal of Asian Natural Products Research, Taylor & Francis, 2010, 73 (10), pp.1706-1707. ⟨10.1021/np1001412⟩
Publication Year :
2010
Publisher :
HAL CCSD, 2010.

Abstract

Research on antifungal compounds from the durable wood from French Guiana Amazonian forest trees highlights the correlation between the activity of their extracts against wood-rotting fungi and human pathogens. The fractionation of an ethyl acetate extract of Sextonia rubra wood led to the isolation of rubrenolide (1) and rubrynolide (2). The potential of compounds 1 and 2 is described through the evaluation of their activity against 16 pathogenic fungi and their cytotoxicity toward NIH-3T3 mammalian fibroblast cells.

Details

Language :
English
ISSN :
01633864, 15206025, and 10286020
Database :
OpenAIRE
Journal :
Journal of Natural Products, Journal of Natural Products, American Chemical Society, 2010, 73 (10), pp.1706-1707. ⟨10.1021/np1001412⟩, Journal of Asian Natural Products Research, Journal of Asian Natural Products Research, Taylor & Francis, 2010, 73 (10), pp.1706-1707. ⟨10.1021/np1001412⟩
Accession number :
edsair.doi.dedup.....8a7413a75be6866fc18efac0fe7a3b4b
Full Text :
https://doi.org/10.1021/np1001412⟩