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Cellulose-based hydrogel beads: Preparation and characterization
- Source :
- Carbohydrate Polymer Technologies and Applications, Vol 2, Iss, Pp 100074-(2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Biopolymer-based hydrogel beads possessing intrinsic low-toxicity, biocompatibility and biodegradability have gained widespread utility in several applications. Among the biopolymers, cellulose is one of the most abundant renewable biomaterials. Herein cellulose hydrogel beads have been prepared by dissolving cellulose in 68% ZnCl2 solution and then crosslinking the polymer chains through calcium ions. The water and ethanol washing of the beads profoundly influences the beads architecture as characterized by Fourier transform infrared spectroscopy, Raman spectroscopy, X-ray powder diffraction and Scanning electron microscopy. The total crystallinity index of the beads increases with the amount of calcium ions that is further enhanced by water washing. These beads, possessing a layer-like nanoporous structure, are capable of loading bovine serum albumin (BSA) and releasing in a sustained manner. The outcome promises a large-scale production of cellulose beads having the potential to be eco-friendly and inexpensive delivery carriers in food, pharmaceutical, medical and agriculture applications.
- Subjects :
- chemistry.chemical_classification
biology
Biocompatibility
Nanoporous
QD415-436
General Medicine
Polymer
engineering.material
Zinc chloride
Biochemistry
Calcium chloride
chemistry.chemical_compound
Crystallinity
chemistry
Chemical engineering
biology.protein
engineering
Biopolymer
Beads
Cellulose
Bovine serum albumin
Fourier transform infrared spectroscopy
Dissolution
Subjects
Details
- ISSN :
- 26668939
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Carbohydrate Polymer Technologies and Applications
- Accession number :
- edsair.doi.dedup.....8a916f5cbec9cbb2a0963accd642c545