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Multiplex PCR assay underreports true bloodstream infections with coagulase-negative staphylococci in hematological patients with febrile neutropenia
- Source :
- Diagnostic Microbiology and Infectious Disease. 85:413-415
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- SeptiFast multiplex PCR assay was evaluated for detecting true bloodstream infections (BSIs) with coagulase-negative staphylococci (CoNS) in neutropenic hematological patients. Sensitivity for samples representing true CoNS-BSIs was 23.3% with an integrated cutoff and increased to 83.3% if the cutoff was neglected. Hence, the cutoff may prohibit timely targeted antimicrobial therapy.
- Subjects :
- Adult
Coagulase
0301 basic medicine
Microbiology (medical)
Staphylococcus
030106 microbiology
Hematologic Neoplasms
Biology
Staphylococcal infections
medicine.disease_cause
Sensitivity and Specificity
Sepsis
03 medical and health sciences
Multiplex polymerase chain reaction
medicine
Humans
Febrile Neutropenia
Bacteriological Techniques
General Medicine
Staphylococcal Infections
medicine.disease
Antimicrobial
Infectious Diseases
Molecular Diagnostic Techniques
Immunology
Multiplex Polymerase Chain Reaction
Febrile neutropenia
Subjects
Details
- ISSN :
- 07328893
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Diagnostic Microbiology and Infectious Disease
- Accession number :
- edsair.doi.dedup.....8ab6cf1b05515d8191420ccc92bccf24