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Zofenopril or irbesartan plus hydrochlorothiazide in elderly patients with isolated systolic hypertension untreated or uncontrolled by previous treatment: a double-blind, randomized study
- Source :
- Journal of hypertension. 34(3)
- Publication Year :
- 2015
-
Abstract
- OBJECTIVE To compare zofenopril + hydrochlorothiazide (Z + H) vs. irbesartan + hydrochlorothiazide (I + H) efficacy on daytime SBP in elderly (>65 years) patients with isolated systolic hypertension (ISH), untreated or uncontrolled by a previous monotherapy. METHODS After a 1-week run-in, 230 ISH patients (office SBP ≥ 140 mmHg and DBP
- Subjects :
- Male
Captopril
Physiology
office blood pressure
Tetrazoles
Blood Pressure
030204 cardiovascular system & hematology
Essential hypertension
Gastroenterology
chemistry.chemical_compound
0302 clinical medicine
Hydrochlorothiazide
zofenopril
030212 general & internal medicine
Blood Pressure Monitoring, Ambulatory
Zofenopril
Biphenyl compound
Treatment Outcome
Hypertension
Cardiology
Drug Therapy, Combination
Female
Cardiology and Cardiovascular Medicine
medicine.drug
medicine.medical_specialty
Ambulatory blood pressure
Systole
NO
03 medical and health sciences
Irbesartan
Vascular Stiffness
Double-Blind Method
Internal medicine
medicine
Internal Medicine
Humans
Antihypertensive Agents
Aged
ambulatory blood pressure monitoring
essential hypertension
hydrochlorothiazide
irbesartan
business.industry
Biphenyl Compounds
medicine.disease
ambulatory blood pressure monitoring, essential hypertension, hydrochlorothiazide, irbesartan, office blood pressure, zofenopril
chemistry
business
Subjects
Details
- ISSN :
- 14735598
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of hypertension
- Accession number :
- edsair.doi.dedup.....8ae3837d097bc88a55926aeb6c1b98df