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Local control of rhino-orbito-cerebral mucormycosis dramatically impacts survival

Authors :
O. Lortholary
Dea Garcia-Hermoso
Philippe Herman
Caroline Elie
Romain Kania
P. Vironneau
Fanny Lanternier
Gloria Morizot
Service d'oto-rhino-laryngologie
Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Lariboisière
Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire (CNRMA)
Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
Service des Maladies infectieuses et tropicales [CHU Necker]
Université Paris Descartes - Paris 5 (UPD5)-CHU Necker - Enfants Malades [AP-HP]-Institut des Maladies Génétiques Imagine [Paris]
CHU Necker - Enfants Malades [AP-HP]
Appendix 1. Members of the French Mycosis Study Group and ENT surgeons in this study Besançon (A. Dussaucy, J.F. Viel, F. Grenouillet, G. Blasco, F. Legrand, J. C. Navellou, E. Plouvier, L. Tavernier, B. Kantelip), Bordeaux (A. Kostrzewa, B. Couprie, J. P. Bebear, E. Blanchart, L. De Gabory, M. Dupon, C. Deminière), Dijon (C. Quantin, D. Caillot, C. Duvillard), Nice (G. Daideri, M. Gari-Toussaint, H. Hyvernat, M. Poiree, P. M. Roger), Nimes (C. Lechiche, L Lachaud), Perpignan (M. Saada, C. Billotet, J.M. Lopez), Rennes (A. Fresnel, X. Carsin, J. P. Gangneux, C. Arvieux, T. Lamy de la Chapelle, N. Rioux), Toulouse (L. Molinier, S. Cassaing, M. Alvarez, L. Esposito, B. Marchou, X. Brousset, E. Uro-Coste, E. Serrano). Those in Paris are as follows: Bichat (C. Chochillon, O. Brugière, M. Wolff, V. Joly, H. Adle- Biassette), Lariboisière (T. Meas, R. Kania, P.Herman, E. Sauvaget), Necker (C. Lebihan, M. E. Bougnoux), Pitié Salpétrière (A. Fekkar, A. Datry, L. Bodin, Y. Samson), Saint-Louis (C. Lacroix, P. Ribaud, A. Xhaard, A. Bergeron-Lafaurie, O. Marie, J. Pavie, E. Raffoux).
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
Source :
Clinical Microbiology and Infection, Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2014, 20 (5), pp.O336-O339. ⟨10.1111/1469-0691.12408⟩, Clinical Microbiology and Infection, 2014, 20 (5), pp.O336-O339. ⟨10.1111/1469-0691.12408⟩
Publication Year :
2014
Publisher :
HAL CCSD, 2014.

Abstract

International audience; Surgery and antifungals are the reference standard for rhino-orbito-cerebral mucormycosis (ROCM) treatment. The impact of local control on survival of 22 consecutive ROCM adults was studied on day 90: none vs. 75% died, respectively, with or without local control (p

Subjects

Subjects :
Male
MESH: Combined Modality Therapy
Antifungal Agents
MESH: Skull Base
MESH: Brain Diseases
MESH: Paranasal Sinus Diseases
Rhino orbito cerebral mucormycosis
mucormycosis
necrosis
surgery
0302 clinical medicine
MESH: Aged, 80 and over
MESH: Bone Diseases, Infectious
Orbital Diseases
030212 general & internal medicine
Sinusitis
[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology
Aged, 80 and over
Skull Base
MESH: Aged
Brain Diseases
0303 health sciences
MESH: Middle Aged
General Medicine
Middle Aged
Bone Diseases, Infectious
Combined Modality Therapy
3. Good health
Survival Rate
Infectious Diseases
MESH: Young Adult
Female
Adult
Microbiology (medical)
medicine.medical_specialty
MESH: Survival Rate
sinusitis
Young Adult
03 medical and health sciences
Paranasal Sinus Diseases
medicine
Humans
MESH: Debridement
Reference standards
Aged
Retrospective Studies
MESH: Mucormycosis
MESH: Humans
MESH: Orbital Diseases
030306 microbiology
business.industry
Mucormycosis
MESH: Adult
MESH: Retrospective Studies
Surgical procedures
medicine.disease
MESH: Antifungal Agents
MESH: Male
Surgery
Debridement
Local control
business
MESH: Female

Details

Language :
English
ISSN :
1198743X and 14690691
Database :
OpenAIRE
Journal :
Clinical Microbiology and Infection, Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2014, 20 (5), pp.O336-O339. ⟨10.1111/1469-0691.12408⟩, Clinical Microbiology and Infection, 2014, 20 (5), pp.O336-O339. ⟨10.1111/1469-0691.12408⟩
Accession number :
edsair.doi.dedup.....8ae8c06ce3e65a29465b24b96f7ef6c9
Full Text :
https://doi.org/10.1111/1469-0691.12408⟩
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