In vitro interactions of licensed and novel antifungal drugs against Fusarium spp

Authors :: Josep Guarro
Javier Capilla
F. Javier Pastor
Montserrat Ortoneda
Isabel Pujol
Source :: Diagnostic Microbiology and Infectious Disease. 48:69-71
Publication Year :: 2004
Publisher :: Elsevier BV, 2004.
Abstract: We have studied the in vitro interactions of amphotericin B (AMB) with terbinafine (TBF), itraconazole, voriconazole (VCZ), albaconazole, and ravuconazole (RVZ), as well as TBF combined with the same azoles, against 11 isolates of Fusarium spp. using the fractional inhibitory concentration index. The highest percentage of synergistic interactions was observed for the combinations AMB-RVZ, TBF-VCZ, and TBF-RCZ.

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