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Characterization of internal ribosome entry sites according to secondary structure analysis to classify Border Disease virus strains
- Source :
- Journal of Virological Methods, Journal of Virological Methods, Elsevier, 2020, 275, pp.113704. ⟨10.1016/j.jviromet.2019.113704⟩
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Applying palindromic nucleotide substitutions (PNS) method, variable loci of the internal ribosome entry site (IRES) secondary structure in the 5' untranslated region (UTR) of Border disease virus sequences were analysed allowing their allocation into ten IRES classes within the species. Sequence characteristics of Turkish and Chinese strains were highly divergent from other genogroups, indicating geographic segregation and micro-evolutive steps within the species. Observed heterogeneity in the BDV species has to be considered for potential implications on diagnostic tests, control and preventive measures.
- Subjects :
- 0301 basic medicine
Untranslated region
Internal ribosome entry site
030106 microbiology
Genome, Viral
Internal Ribosome Entry Sites
Biology
Border disease virus
03 medical and health sciences
Secondary structure
Virology
Animals
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Protein secondary structure
Phylogeny
Sequence (medicine)
Genetics
Inverted Repeat Sequences
Palindrome
Diagnostic test
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
030104 developmental biology
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Nucleic Acid Conformation
RNA, Viral
5' Untranslated Regions
Subjects
Details
- Language :
- English
- ISSN :
- 01660934
- Database :
- OpenAIRE
- Journal :
- Journal of Virological Methods, Journal of Virological Methods, Elsevier, 2020, 275, pp.113704. ⟨10.1016/j.jviromet.2019.113704⟩
- Accession number :
- edsair.doi.dedup.....8bac7e7202e0d5fa323b52e1713ce80e
- Full Text :
- https://doi.org/10.1016/j.jviromet.2019.113704⟩