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Cost-Utility of a Single-Injection Combined Corticosteroid-Hyaluronic Acid Formulation vs a 2-Injection Regimen of Sequential Corticosteroid and Hyaluronic Acid Injections
- Source :
- Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders, Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, Vol 10 (2017)
- Publication Year :
- 2017
- Publisher :
- SAGE Publications, 2017.
-
Abstract
- Research has shown early and sustained relief with a combination therapy of a corticosteroid (CS) and hyaluronic acid (HA) in knee osteoarthritis (OA) patients. This can be administered via a single injection containing both products or as separate injections. The former may be more expensive when considering only product cost, but the latter incurs the additional costs and time of a second procedure. The purpose of this study was to compare the cost-utility of the single injection with the 2-injection regimen. The results of this analysis revealed that the single-injection formulation of a CS and HA may be cost-effective, assuming a willingness-to-pay of $50 000 per quality-adjusted life year gained, for symptomatic relief of OA symptoms. This treatment may also be more desirable to patients who find injections to be inconvenient or unpleasant.
- Subjects :
- lcsh:Diseases of the musculoskeletal system
Combination therapy
medicine.drug_class
Osteoarthritis
Bioinformatics
corticosteroids
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Rheumatology
Hyaluronic acid
hyaluronic acid
Immunology and Allergy
Medicine
030212 general & internal medicine
cost-utility
health care economics and organizations
Original Research
030203 arthritis & rheumatology
business.industry
Single injection
medicine.disease
Symptomatic relief
Regimen
chemistry
Anesthesia
Drug delivery
Corticosteroid
Knee osteoarthritis
lcsh:RC925-935
business
Subjects
Details
- Language :
- English
- ISSN :
- 11795441
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
- Accession number :
- edsair.doi.dedup.....8bacc30cee5bcffafa71891be72959e1