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Outcomes of inpatient cholecystectomy among adults with cystic fibrosis in the United States
- Source :
- World Journal of Gastrointestinal Endoscopy
- Publication Year :
- 2021
- Publisher :
- Baishideng Publishing Group Inc, 2021.
-
Abstract
- BACKGROUND Symptomatic biliary and gallbladder disorders are common in adults with cystic fibrosis (CF) and the prevalence may rise with increasing CF transmembrane conductance regulator modulator use. Cholecystectomy may be considered, but the outcomes of cholecystectomy are not well described among modern patients with CF. AIM To determine the risk profile of inpatient cholecystectomy in patients with CF. METHODS The Nationwide Inpatient Sample was queried from 2002 until 2014 to investigate outcomes of cholecystectomy among hospitalized adults with CF compared to controls without CF. A propensity weighted sample was selected that closely matched patient demographics, patient's individual comorbidities, and hospital characteristics. The propensity weighted sample was used to compare outcomes among patients who underwent laparoscopic cholecystectomy. Hospital outcomes of open and laparoscopic cholecystectomy were compared among adults with CF. RESULTS A total of 1239 inpatient cholecystectomies were performed in patients with CF, of which 78.6% were performed laparoscopically. Mortality was < 0.81%, similar to those without CF (P = 0.719). In the propensity weighted analysis of laparoscopic cholecystectomy, there was no difference in mortality, or pulmonary or surgical complications between patients with CF and controls. After adjusting for significant covariates among patients with CF, open cholecystectomy was independently associated with a 4.8 d longer length of stay (P = 0.018) and an $18449 increase in hospital costs (P = 0.005) compared to laparoscopic cholecystectomy. CONCLUSION Patients with CF have a very low mortality after cholecystectomy that is similar to the general population. Among patients with CF, laparoscopic approach reduces resource utilization and minimizes post-operative complications.
- Subjects :
- medicine.medical_specialty
education.field_of_study
business.industry
Patient demographics
medicine.medical_treatment
Population
medicine.disease
Symptomatic biliary disorders
Cystic fibrosis
Laparoscopic cholecystectomy
Hospital outcomes
Nationwide Inpatient Sample
Retrospective Study
Internal medicine
medicine
Length of stay
Cholecystectomy
In patient
Mortality
business
education
Resource utilization
Subjects
Details
- Language :
- English
- ISSN :
- 19485190
- Volume :
- 13
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- World Journal of Gastrointestinal Endoscopy
- Accession number :
- edsair.doi.dedup.....8c899acb02e0f4cb70262239e185acc9