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Elastic tissue damage in cephalic acquired cutis laxa
- Source :
- Journal of cutaneous pathology. 35(1)
- Publication Year :
- 2007
-
Abstract
- Cutis laxa is a rare condition characterized by diminished elastic tissue. We report the histological changes from a 22-year-old male patient, who presented since 4 years hanging and inelastic facial skin, giving him an older appearance. The palpebral, preauricular and submandibular skin obtained after a facelift were examined. Conventional light microscopy with hematoxylin-eosin staining showed perivascular lymphocytic infiltrates and crossed-over collagen fibers. With Weigert staining, a lessening of elastic fibers with fragmentation, shortening and clumping was seen. The oxytalanic fibers in the papillary dermis were also affected, ranging from absence or reduction to flattening with clumping of the fibers, giving an irregular contour to the basal membrane zone. These findings were more intense in the palpebral skin. Transmission electronic microscopy showed reduction of the elastic fibers, a granular degeneration of the elastic tissue was found and collagen fibers were normal. Similar to light microscopy, at the ultrastructural level, the basal membrane has an irregular contour.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Histology
Dermatology
Cutis Laxa
Pathology and Forensic Medicine
Lymphocytic Infiltrate
Microscopy, Electron, Transmission
Microscopy
Medicine
Humans
Surgery, Plastic
Staining and Labeling
business.industry
Papillary dermis
Anatomy
medicine.disease
Elastic Tissue
Staining
Palpebral fissure
Treatment Outcome
Ultrastructure
Acquired cutis laxa
business
Head
Cutis laxa
Subjects
Details
- ISSN :
- 16000560
- Volume :
- 35
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of cutaneous pathology
- Accession number :
- edsair.doi.dedup.....8cbb7ed23be42ebbc771dc73d8862548