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Paper-Based Point-of-Care Testing of SARS-CoV-2
- Source :
- Frontiers in Bioengineering and Biotechnology, Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
- Publication Year :
- 2021
- Publisher :
- Frontiers Media S.A., 2021.
-
Abstract
- The COVID-19 pandemic has resulted in significant global social and economic disruption. The highly transmissive nature of the disease makes rapid and reliable detection critically important. Point-of-care (POC) tests involve performing diagnostic tests outside of a laboratory that produce a rapid and reliable result. It therefore allows the diagnostics of diseases at or near the patient site. Paper-based POC tests have been gaining interest in recent years as they allow rapid, low-cost detection without the need for external instruments. In this review, we focus on the development of paper-based POC devices for the detection of SARS-CoV-2. The review first introduces the principles of detection methods that are available to paper-based devices. It then summarizes the state-of-the-art paper devices and their analytical performances. The advantages and drawbacks among methods are also discussed. Finally, limitations of the existing devices are discussed, and prospects are given with the hope to identify research opportunities and directions in the field. We hope this review will be helpful for researchers to develop a clinically useful and economically efficient paper-based platform that can be used for rapid, accurate on-site diagnosis to aid in identifying acute infections and eventually contain the COVID-19 pandemic.
- Subjects :
- Histology
Coronavirus disease 2019 (COVID-19)
Computer science
COVID-19 diagnostics
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Point-of-care testing
Biomedical Engineering
Diagnostic test
Bioengineering and Biotechnology
Bioengineering
Paper based
Research opportunities
Review
paper-based
Field (computer science)
Risk analysis (engineering)
point-of-care
CRISPR
immunoassay
TP248.13-248.65
Biotechnology
Point of care
Subjects
Details
- Language :
- English
- ISSN :
- 22964185
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Frontiers in Bioengineering and Biotechnology
- Accession number :
- edsair.doi.dedup.....8ccbe7cd52f7d14c2baba65a4e4eea20