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Sarcomatoid carcinoma arising in the congenital pigmented nevus after treatment with carbon dioxide snow freezing method
- Source :
- The Journal of dermatology. 42(11)
- Publication Year :
- 2014
-
Abstract
- We report a case of sarcomatoid carcinoma of the skin in a 63-year-old man who was treated with the carbon dioxide snow freezing method for a huge congenital pigmented nevus that extended from the right upper extremity to the right trunk during childhood. He had an exophytic red tumor on the nevus in the right upper extremity that grew slowly for 4 years and rapidly recently. Histological and immunohistochemical studies revealed both epithelial and mesenchymal malignancy in the same tumor. The epithelial component was composed of basaloid cells forming multiple nests with peripheral palisading, positive for keratins and BerEP4, implying basal cell carcinoma. The mesenchymal component was composed of spindle-shaped cells negative for keratins and positive for vimentin, suggesting sarcoma. This is, to our knowledge, the first report of sarcomatoid carcinoma arising in the primary pigmented nevus that had been treated by the carbon dioxide snow freezing method.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Skin Neoplasms
Vimentin
Dermatology
Biology
Malignancy
Dry Ice
medicine
Carcinoma
Pigmented Nevus
Nevus
Humans
Basal cell carcinoma
Sarcomatoid carcinoma
Nevus, Pigmented
Neoplasms, Second Primary
Sarcoma
General Medicine
Anatomy
Middle Aged
medicine.disease
Carcinoma, Basal Cell
biology.protein
Subjects
Details
- ISSN :
- 13468138
- Volume :
- 42
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- The Journal of dermatology
- Accession number :
- edsair.doi.dedup.....8d0a81f727b661be1c6024602ea043bb