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A portable digital optical kanamycin sensor developed by surface-anchored liquid crystal droplets
- Source :
- Journal of Hazardous Materials. 420:126601
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- There is an increase in demand to develop simple, convenient, and low-cost approaches for rapid and label-free detection of antibiotics. Herein, we propose a new principle for the detection of kanamycin using the surface-anchored liquid crystal (LC) droplets. The optical images of the LC droplets uniformly change from four-clover, uniformly dark, and dark cross appearance gradually with the increase of surfactant concentration. The detection of kanamycin is fulfilled with the aid of a cationic surfactant cetyltrimethylammonium bromide (CTAB) and a kanamycin aptamer. The LC droplets show uniformly dark appearance and four-clover appearance in the presence of the aqueous solutions of CTAB and CTAB/aptamer complex, respectively. However, the specific binding of kanamycin to its aptamer can release the CTAB, which induces the uniformly dark appearance of the LC droplets. A portable device is built to measure the optical luminance of the LC droplets. This system can detect kanamycin with a concentration below 0.1 ng/mL (~0.17 nM) and also allows the detection of kanamycin in real samples such as milk and honey. Therefore, it is very promising in the development of new types of LC-based sensors by the surface-anchored LC droplets assisted with a portable optical device.
- Subjects :
- Environmental Engineering
Materials science
Health, Toxicology and Mutagenesis
Aptamer
Surface-Active Agents
chemistry.chemical_compound
Pulmonary surfactant
Kanamycin
Liquid crystal
Bromide
medicine
Animals
Environmental Chemistry
Waste Management and Disposal
Aqueous solution
Chromatography
Liquid crystal droplet
Cationic polymerization
food and beverages
Pollution
eye diseases
Anti-Bacterial Agents
Liquid Crystals
Milk
chemistry
medicine.drug
Subjects
Details
- ISSN :
- 03043894
- Volume :
- 420
- Database :
- OpenAIRE
- Journal :
- Journal of Hazardous Materials
- Accession number :
- edsair.doi.dedup.....8d67d02db052bb9fa8a57b6120a7466b