Supplementary Figures 1 - 12 from Role of WNT7B-induced Noncanonical Pathway in Advanced Prostate Cancer

PDF file - 3153K, Figure S1. WNT7B is regulated by the AR in CRPC 22RV1 cells. Figure S2. TUNEL assays after WNT7B knockdown. Figure S3. Knockdown efficiency of WNT7B shRNA determined by RT-qPCR. Figure S4. WNT7B is required for 22RV1 cell growth. Figure S5. WNT7B is overexpressed in CRPC tumors. Figure S6. β-Catenin distribution in C4-2B cells. Figure S7. PKCα and PKCδ are direct AR target genes in C4-2B cells. Figure S8. WNT7B promotes osteoblast differentiation of ST2 and C3H10T1/2 cells. Figure S9. Insoluble WNT7B is bound to the cell membrane. Figure S10. Mouse ALP, BSP and GAPDH primers are specific for mouse genes. Figure S11. PC-produced WNT7B promotes ST2 osteoblast differentiation. Figure S12. PC-produced WNT7B promotes C3H10T1/2 osteoblast differentiation.