MOESM1 of LINE-1 ORF2p expression is nearly imperceptible in human cancers

Additional file 1: Figure S1. CLUSTAL Alignments of ORF2 protein sequences. ORF2p protein sequences were obtained from the L1Base database of reference L1Hs sequences. (A) Alignment of 146 full-length L1 sequences. (B) Alignment of 107 ORF2-intact L1 sequences. In the center tiles, black bars indicate amino acid positions where the L1 in that row differs from the CLUSTAL alignment consensus sequence. The ‘% agreement,’ or identity, at each amino acid position is quantified below the center tiles. On the right, the number of amino acid changes of a particular L1 compared to the immunogen, L1RP, is quantified.