Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection

Authors :: Robin L. Dewar
Perrine Lallemand
Suteeraporn Pinyakorn
Donn J Colby
Jintanat Ananworanich
Tippawan Pankam
Catherine W. Cai
Mark de Souza
Adam Rupert
Sandhya Vasan
Irini Sereti
Supanit Pattanachaiwit
Eugene Kroon
Helene C Highbarger
Sasiwimol Ubolyam
Graduate School
AII - Infectious diseases
APH - Aging & Later Life
Global Health
Source :: Open forum infectious diseases, 7(9):ofaa383. Oxford University Press, Open Forum Infect Dis
Publication Year :: 2020
Publisher :: Oxford University Press (OUP), 2020.
Abstract: Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic inflammation in early treated PWH.

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