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In situ-synthesized cadmium sulfide nanowire photosensor with a parylene passivation layer for chemiluminescent immunoassays
- Source :
- Biosensors and Bioelectronics. 92:221-228
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- The direct in situ synthesis of cadmium sulfide (CdS) nanowires (NWs) was presented by direct synthesis of CdS NWs on the gold surface of an interdigitated electrode (IDE). In this work, we investigated the effect of a strong oxidant on the surfaces of the CdS NWs using X-ray photoelectron spectroscopy, transmission electron microscopy, and time-of-flight secondary ion mass spectrometry. We also fabricated a parylene-C film as a surface passivation layer for in situ-synthesized CdS NW photosensors and investigated the influence of the parylene-C passivation layer on the photoresponse during the coating of parylene-C under vacuum using a quartz crystal microbalance and a photoanalyzer. Finally, we used the in situ-synthesized CdS NW photosensor with the parylene-C passivation layer to detect the chemiluminescence of horseradish peroxidase and luminol and applied it to medical detection of carcinoembryonic antigen.
- Subjects :
- Materials science
Passivation
Polymers
Biomedical Engineering
Biophysics
Analytical chemistry
Nanowire
Biosensing Techniques
02 engineering and technology
Sulfides
Xylenes
010402 general chemistry
01 natural sciences
chemistry.chemical_compound
X-ray photoelectron spectroscopy
Parylene
Cadmium Compounds
Electrochemistry
Humans
Horseradish Peroxidase
Immunoassay
Luminescent Agents
Nanowires
business.industry
Equipment Design
General Medicine
Quartz crystal microbalance
021001 nanoscience & nanotechnology
Cadmium sulfide
Carcinoembryonic Antigen
0104 chemical sciences
Secondary ion mass spectrometry
chemistry
Luminescent Measurements
Optoelectronics
Luminol
0210 nano-technology
business
Oxidation-Reduction
Layer (electronics)
Biotechnology
Subjects
Details
- ISSN :
- 09565663
- Volume :
- 92
- Database :
- OpenAIRE
- Journal :
- Biosensors and Bioelectronics
- Accession number :
- edsair.doi.dedup.....8fbb374ab11a352f875b3f110e95ddaf