Humanized mice for investigating SARS‐CoV‐2 lung infection and associated human immune responses

Authors :: Renren Sun
Zongzheng Zhao
Cong Fu
Yixin Wang
Zhendong Guo
Chunmao Zhang
Lina Liu
Cheng Zhang
Chang Shu
Jin He
Yong‐Guang Yang
Shucheng Hua
Yuwei Gao
Zheng Hu
Source :: European Journal of Immunology. 52:1640-1647
Publication Year :: 2022
Publisher :: Wiley, 2022.
Abstract: There is an urgent need for animal models of coronavirus disease 2019 to study immunopathogenesis and test therapeutic intervenes. In this study, we showed that NOD/SCID IL2rg

Subjects :: SARS-CoV-2
Immunology
Immunity
COVID-19
Mice, SCID
Disease Models, Animal
Mice
Mice, Inbred NOD
Chlorocebus aethiops
Animals
Humans
RNA
Immunology and Allergy
Lung
Vero Cells

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