Back to Search
Start Over
Development of a brief clinician-reported outcome measure of multiple sclerosis signs and symptoms: The Clinician Rating of Multiple Sclerosis (CRoMS)
- Source :
- Multiple Sclerosis and Related Disorders. 35:253-261
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Objective No available assessment tool offers a brief and psychometrically sound way for clinicians to quantify assessment of MS in a typical office visit. The objective of this study was to develop a brief clinician-reported outcome measure of MS signs and symptoms to standardize and quantify assessments that occur during a typical neurology office visit. Methods A questionnaire, called the Clinician Rating of Multiple Sclerosis (CRoMS), was developed in the following steps: literature review; concept elicitation interviews (to generate questionnaire themes and content) with patients with MS (n=14); concept elicitation interviews with neurologists (n=9); online qualitative survey with neurologists in the US, UK, Germany, and Sweden (n=72); online survey with neurologists to evaluate the first draft of the ClinRO (n=26); an in-person meeting with neurologists to discuss and revise the draft ClinRO (n=9); and interviews with neurologists and MS nurses to further refine and finalize the ClinRO (n=16). Results Across all steps of this research, several signs and symptoms consistently emerged as important for assessment in a typical office visit: walking, balance, upper limb function, coordination, weakness, fatigue, pain, sensory symptoms, bladder function, visual function, cognition, spasticity, spasms, and mood. The importance of these signs and symptoms was supported by neurologists during the online surveys and the in-person meeting. Neurologists were generally able to complete the draft ClinRO measure without difficulty, although minor revisions were suggested to refine the ClinRO for future use. Conclusion The CRoMS may be a useful tool for efficiently assessing the severity of MS symptoms. This brief clinician-reported measure could help standardize and quantify assessments in clinical studies and clinical settings.
- Subjects :
- Adult
Male
medicine.medical_specialty
Multiple sclerosis signs and symptoms
Weakness
Multiple Sclerosis
Neurology
Psychometrics
Walking
Severity of Illness Index
03 medical and health sciences
0302 clinical medicine
Germany
Surveys and Questionnaires
Outcome Assessment, Health Care
Humans
Medicine
Sensory symptoms
030212 general & internal medicine
Postural Balance
Fatigue
Sweden
business.industry
Multiple sclerosis
Outcome measures
Cognition
General Medicine
Middle Aged
medicine.disease
United Kingdom
United States
Mood
Physical therapy
Female
Neurology (clinical)
Symptom Assessment
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 22110348
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Multiple Sclerosis and Related Disorders
- Accession number :
- edsair.doi.dedup.....90b2735a9829c4962b0f7063b838b4e7