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New insights into the fascinating world of glucocorticoids: the dexamethasone-miR-342-Rictor axis in regulatory T cells
- Source :
- Cellular & molecular immunology, 18(3):520522, Cellular and Molecular Immunology
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here, utilizing murine autoimmune and allergic inflammation models, we report that Foxp3
- Subjects :
- Immunology
Anti-Inflammatory Agents
Mechanistic Target of Rapamycin Complex 2
Biology
T-Lymphocytes, Regulatory
Dexamethasone
Mice
Receptors, Glucocorticoid
Text mining
medicine
Animals
Immunology and Allergy
Glucocorticoids
Inflammation
business.industry
Forkhead Transcription Factors
Research Highlight
Mice, Inbred C57BL
MicroRNAs
Cell signalling
Rapamycin-Insensitive Companion of mTOR Protein
Infectious Diseases
Cancer research
business
medicine.drug
Subjects
Details
- ISSN :
- 20420226 and 16727681
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Cellular & Molecular Immunology
- Accession number :
- edsair.doi.dedup.....911ae5979c791892d3a9d21d19e3b508